In 2010, when Lilli Holst scraped a lump of soil from the underside of a rotting eggplant, she had no idea that this act would help to save the life of a British teenager, eight years later and 6,000 miles away.
AbstractThe emergence of multiple drug-resistant bacteria has prompted interest in alternatives to conventional antimicrobials. One of the possible replacement options for antibiotics is the use of bacteriophages as antimicrobial agents. Phage therapy is an important alternative to antibiotics in the current era of drug-resistant pathogens. Bacteriophages have played an important role in the expansion of molecular biology and have been used as antibacterial agents since 1966. In this review, we describe a brief history of bacteriophages and clinical studies on their use in bacterial disease prophylaxis and therapy. We discuss the advantages and disadvantages of bacteriophages as therapeutic agents in this regard.
This year millions of people around the world have radically changed their way of life to avoid contact with other people and, thus, the novel coronavirus. Despite social distancing, many have still gotten sick in part from other viral infections. That is because, as scientists are increasingly learning, many viruses are lurking quietly in the human body, hidden away in cells in the lungs, blood and nerves and inside the multitudes of microbes that colonize our gut.
At the same time that the antibiotic era is running into serious problems because of antibiotic resistance, we may be at the dawn of the era of phage therapy for bacterial infections. But phage therapy is actually over a century old, so what we are seeing is the rebirth of phage therapy with far more advanced technology for biologics in general, and genetic manipulation specifically. Further, the combination of antibiotic and phage therapy may be particularly potent.But the history of phage therapy also tells us that we cannot get so caught up in the hype that we skip over careful and rigorous clinical research.
What is interesting about bacteriophages and other viruses in the gut is that every person has their own unique set, with almost no overlap between two different people.
“Munchausen by internet” is rattling tight-knit online support groups
It’s a form of factitious disorder, the mental disorder formerly known as Munchausen syndrome, in which people feign illness or actually make themselves sick for sympathy and attention.
From a Three-Pianos Concert with Corea-Gulda-Economou. Munchner Klavier Sommer 1982.
Wow. That's a pile of books.
According to the Republic of Ireland's Copyright and Related Rights Act, 2000, the Library is entitled, along with the National Library of Ireland and the libraries of the National University of Ireland, the University of Limerick, and Dublin City University, to receive a copy of all works published in the Republic of Ireland. Also, as a result of the British Legal Deposit Libraries Act 2003, which continues a more ancient right dating from 1801, the Library is entitled, along with the British Library, the Bodleian Library at Oxford, Cambridge University Library, the National Library of Wales and the National Library of Scotland, to receive a copy on request of all works published in the United Kingdom.
It's a wonderful library, and you can see The Book of Kells.
The Book of Kells (Digitalcollection, Trinity College Dublin)+-- Book of Kells (Wikipedia)
A sort of news and novelty collector for Zot people and community
Once upon a time, offices had walls inside them. They weren’t glass, like the conference rooms of 2019, but were made of drywall, and were usually painted a neutral color, like many of the walls you know and love. Over time, office walls gave way to cubicles. Now, for many office workers, the cubicles are also gone. There are only desks.If you’re under 40, you might have never experienced the joy of walls at work.
In the open-plan office, wireless headphones are the new cubicles.
..has ushered in a new era of office etiquette—and created a whole new set of problems.
