Is this a right decision to make sets without humans? For 15 years we keep hearing that Lorwyn didn’t do well due to lack of humans for players to associate themselves with.I'm just a freelancer, so I don't have any access to their market research or the reasoning for their decisions to do a set, but I think there are some obvious differences here.
First is that Lorwyn was four sets long, the longest period of time spent on any plane in a row since Dominaria.
Second is that single set returns are vastly different than block returns were, that's how we got Kamigawa, and how we're getting a new Lorwyn set.
Third is that they're embracing keeping the creative for a world but changing the mechanical, so if their concern was partially about a Lorwyn typal block they can vary it up.
Finally, anthropomorphic animals are way different than a regular fantasy environment sans humans. There's tons of media that features them.
